Klinik Öncesi Bölümler

Preclinical Science

Department of Pharmacology and Toxicology

(Course Contents)

Preclinical Science

PHARMACOLOGY-I

WEEKS
1	THEORECTICAL	Definition of pharmacology and drug concepts, sources of drugs, classification, naming, structure-effect relationship
	PRATICAL	Pharmaceutical processes, measurement and weighing (Molarity, Normality,% Calculation, ppm, ppb mg / kg, mg / ml)
2	THEORECTICAL	Pharmacokinetics (ways of using drugs and absorption, distribution of drugs, changes in the body of drugs, discarding drugs)
	PRACTICAL	Liquid drug forms and tenture diode preparation
3	THEORECTICAL	The effect of drugs, Dose-Density and Dose-Effect relationship, interactions between drugs, factors affecting the effect of drugs, drug resistance and dependence, undesirable effects of drugs
	PRACTICAL	Semi-solid drug forms and glycerin iodine preparation
4	THEORECTICAL	Prescription writing, licensing of veterinary drugs and legislation
	PRACTICAL	Demonstration of sample prescription writing
5	THEORECTICAL	Classification of chemotherapeutics, introduction to antibiotics (antibacterial activity, spectrum of action, potency, mode of action, antibacterial resistance, antibiotic mixtures)
	PRACTICAL	Pharmacopoeia and Prospectus Examination
6	THEORECTICAL	Beta lactam, aminoglycoside and macrolide antibiotics properties, classification, pharmacokinetics, mode of action, effect spectrum, side / toxic effects and uses
	PRACTICAL	Sample prescription writing in antibacterial diseases-I
7	THEORECTICAL	Properties of tetracycline, phenicol, linkosamide, polypeptide, and quinolone antibiotics
	PRACTICAL	Sample prescription writing in antibacterial diseases-II
8	THEORECTICAL	Nitrofurans, Imidazoles, Rifamycins, Sulfonamides, properties, classification, pharmacokinetics, types of action, effect spectra, side / toxic effects and uses of antibiotics. Antibiotics used in some diseases.
	PRACTICAL	Sample prescription writing in antibacterial diseases-III
9	THEORECTICAL	-Exam Properties, classifications, pharmacokinetics, types of action, effect spectrum, side / toxic effects and uses of anthelmintic drugs. Use of strategic anthelmintics. -Properties, classification, pharmacokinetics, modes of action, effect spectra, side / toxic effects and uses of drugs affecting protozoa
	PRACTICAL	Sample prescribing in internal parasitic and protozoal diseases.
10	THEORECTICAL	Introduction to drugs that affect external parasites (external parasites living in the body, forms of drug administration, precautions to be taken into consideration when using the drug, properties, types of action of insecticides, classification) -Insecticides, Insect growth regulators, Inorganic drugs, Plant-based drugs, Microbial drugs and Biological properties, classification, pharmacokinetics, mode of action, toxicity and treatment options. Drug selection by type and type of animal
	PRACTICAL	Sample prescribing in the fight against external parasites
11	THEORECTICAL	Insect repellents, drugs used against rodents and classification of drugs used against slugs, their properties, mode of action, effects and uses. Control of important insects in terms of public health. Insecticide formulations, methods of application, Selection of an appropriate chemical control strategy, resistance to insecticides.
	PRACTICAL	Writing a sample prescription in the fight against insects, rodents and slugs
12	THEORECTICAL	Mosquitoes, Fly Flies, Cockroaches, Fleas, Wooden Crops, Lice, Mites, Fight against poisonous arthropods
	PRACTICAL	Sample prescription writing in the fight against mosquitoes, volatile flies, cockroaches, fleas, wood chips, lice, mites and poisonous arthropods
13	THEORECTICAL	Classification, properties, effects and uses of drugs affecting fungi and viruses
	PRACTICAL	Sample prescription writing in fungal and viral diseases
14	THEORECTICAL	Classification of antiseptics and disinfectants, their properties, types of action, effect spectra, usage, classification and disinfection.
	PRACTICAL	Introduction and usage examples of antiseptics and disinfectants
15	THEORECTICAL	Neoplastic Diseases Chemotherapy, properties of drugs used, classification, side effects, warnings, toxicity, resistance and use.
	PRACTICAL	Sample prescription writing in chemotherapy of neoplastic diseases

PHARMACOLOGY-II

WEEKS
1	THEORECTICAL	General anesthetics, anticonvulsant, classification of sedative and sleep drugs, chemical properties, pharmacokinetics (absorption, distribution, metabolism and excretion) and pharmacodynamic properties (effects and mechanism of action), side / harmful effects, principles of use.
	PRACTICAL	Sample prescriptions writing about general anesthetics, anticonvulsant, sedative and sleeping drugs.
2	THEORECTICAL	Psychotropic drugs, central effect muscle relaxants and local anesthetic drugs classification, chemical properties, pharmacokinetics (absorption, distribution, metabolism and excretion) and pharmacodynamic properties (effects and mechanism of action), side / harmful effects, principles of use.
	PRACTICAL	Sample prescriptions writing about psychotropic drugs, central effect muscle relaxants and local anesthetic drugs.
3	THEORECTICAL	Narcotic and non-narcotic pain medication, central nervous system stimulating drugs, classification, chemical properties, pharmacokinetics (absorption, distribution, metabolism and excretion) and pharmacodynamic properties (effects and mechanism of action), side / harmful effects, principles of use.
	PRACTICAL	Sample prescriptions writing about narcotics and non-narcotic pain medication, central nervous system stimulating drugs.
4	THEORECTICAL	Sympathomimetic, sympatholytic drugs and autonomic ganglia drugs, classification, chemical properties, pharmacokinetics (absorption, distribution, metabolism and excretion) and pharmacodynamic properties (effects and mechanism of action), side / harmful effects, principles of use.
	PRACTICAL	Sample prescriptions writing about sympathomimetic, sympatholytic and autonomic ganglia drugs.
5	THEORECTICAL	Parasympathomimetic, parasympatholytic, neuromuscular blocking drugs classification, chemical properties, pharmacokinetics (absorption, distribution, metabolism and excretion) and pharmacodynamic properties (effects and mechanism of action), side / harmful effects, principles of use.
	PRACTICAL	Sample prescriptions writing about parasympathomimetic, parasympatholytic, neuromuscular blocking drugs.
6	THEORECTICAL	Cardiovascular system drugs classification, chemical properties, pharmacokinetics (absorption, distribution, metabolism and excretion) and pharmacodynamic properties (effects and mechanism of action), side / harmful effects, principles of use.
	PRACTICAL	Sample prescriptions writing about cardiovascular system drugs.
7	THEORECTICAL	Drugs affecting blood and blood forming structures, classification, chemical properties, pharmacokinetics (absorption, distribution, metabolism and excretion) and pharmacodynamic properties (effects and mechanism of action), side / harmful effects, principles of use.
	PRACTICAL	Sample prescriptions writing about drugs affecting blood and blood forming structures.
8	THEORECTICAL	Local hormones classification, chemical properties, pharmacokinetics (absorption, distribution, metabolism and excretion) and pharmacodynamic properties (effects and mechanism of action), side / harmful effects, principles of use.
	PRACTICAL	Sample prescriptions writing about local hormones.
9	THEORECTICAL	Exam -Hormonal system drugs classification, chemical properties, pharmacokinetics (absorption, distribution, metabolism and excretion) and pharmacodynamic properties (effects and mechanism of action), side / harmful effects, principles of use.
	PRACTICAL	Sample prescriptions writing about hormonal system drugs
10	THEORECTICAL	Liquid electrolyte and acid base balance system drugs classification, chemical properties, pharmacokinetics (absorption, distribution, metabolism and excretion) and pharmacodynamic properties (effects and mechanism of action), side / harmful effects, principles of use.
	PRACTICAL	Sample prescriptions writing about liquid electrolyte and acid base balance system drugs.
11	THEORECTICAL	Respiratory system drugs classification, chemical properties, pharmacokinetics (absorption, distribution, metabolism and excretion) and pharmacodynamic properties (effects and mechanism of action), side / harmful effects, principles of use.
	PRACTICAL	Sample prescriptions writing about respiratory system drugs.
12	THEORECTICAL	Digestive system drugs classification, chemical properties, pharmacokinetics (absorption, distribution, metabolism and excretion) and pharmacodynamic properties (effects and mechanism of action), side / harmful effects, principles of use.
	PRACTICAL	Sample prescriptions writing about digestive system drugs
13	THEORECTICAL	Vitamins, minerals and growth promoters classification, chemical properties, pharmacokinetics (absorption, distribution, metabolism and excretion) and pharmacodynamic properties (effects and mechanism of action), side / harmful effects, principles of use.
	PRACTICAL	Sample prescriptions writing about vitamins, minerals and growth promoters.
14	THEORECTICAL	Homeopathic medicines and herbs classification, chemical properties, pharmacokinetics (absorption, distribution, metabolism and excretion) and pharmacodynamic properties (effects and mechanism of action), side / harmful effects, principles of use.
	PRACTICAL	Sample prescriptions writing about homeopathic medicines and herbs.
15	THEORECTICAL	-Immune system drugs classification, chemical properties, pharmacokinetics (absorption, distribution, metabolism and excretion) and pharmacodynamic properties (effects and mechanism of action), side / harmful effects, principles of use. - Drug residues in foods, residual problems in animals / animal products entering the human food chain, legal regulations and withdrawal time.
	PRACTICAL	- Sample prescriptions writing about immune system drugs - Prescription of the periods that should not be used after the use of drugs

TOXICOLOGY

WEEKS
1	THEORECTICAL	Toxicology and poison concepts's definition, types of poisoning, effects of poisons and interactions between poisons, poisoning and toxicity tests.
	PRACTICAL	Laboratory materials introduction, usage and information.
2	THEORECTICAL	Dose-density and dose-effect relationship, poisoning and factors affecting toxicity.
	PRACTICAL	Chemical substances used in the laboratory introduction, properties, label information and possible interaction risks
3	THEORECTICAL	Toxicokinetics (absorption, distribution, biotransformation and excretion).
	PRACTICAL	Sampling for diagnosis and analysis and sending to laboratory, preparing general purpose report, examining related regulations and communiques in poisoning.
4	THEORECTICAL	Poisons mode of action, causes of poisoning, diagnosis and treatment.
	PRACTICAL	Processing, evaluation and report preparation of samples coming to the laboratory for analysis.
5	THEORECTICAL	Metals
	PRACTICAL	In metal intoxications, taking anamnesis, sending morbid substance to laboratory for diagnosis, keeping report, preparing report and applying treatment principles.
6	THEORECTICAL	Other inorganic substances and radioactive substances.
	PRACTICAL	In other inorganic substances and radioactive substances intoxications, taking anamnesis, sending morbid substance to laboratory for diagnosis, keeping report, preparing report and applying treatment principles.
7	THEORECTICAL	Organic substances, toxic gases, vapors and particles
	PRACTICAL	In organic substances, toxic gases, vapors and particles intoxications, taking anamnesis, sending morbid substance to laboratory for diagnosis, keeping report, preparing report and applying treatment principles.
8	THEORECTICAL	Herbal poisons
	PRACTICAL	In herbal intoxications, taking anamnesis, sending morbid substance to laboratory for diagnosis, keeping report, preparing report and applying treatment principles.
9	THEORECTICAL	Insecticides, rat poisons, molluscicides, fungicides
	PRACTICAL	In insecticides, rat poisons, molluscicides, fungicides intoxications, taking anamnesis, sending morbid substance to laboratory for diagnosis, keeping report, preparing report and applying treatment principles.
10	THEORECTICAL	Weed drugs, herbicides, plant growth regulators, algicides
	PRACTICAL	Weed drugs, herbicides, plant growth regulators, algicides intoxications, taking anamnesis, sending morbid substance to laboratory for diagnosis, keeping report, preparing report and applying treatment principles.
11	THEORECTICAL	Mycotoxins
	PRACTICAL	Mycotoxin intoxications, taking anamnesis, sending morbid substance to laboratory for diagnosis, keeping report, preparing report and applying treatment principles.
12	THEORECTICAL	Large fungal poisons, poisonous animals and poisons
	PRACTICAL	Large fungal poisons, poisonous animals and poisons intoxications, taking anamnesis, sending morbid substance to laboratory for diagnosis, keeping report, preparing report and applying treatment principles.
13	THEORECTICAL	Substances used for doping, capture and humane killing of animals
	PRACTICAL	Sample sending to the laboratory, report keeping and report preparation for doping. Selection of appropriate substances for euthanasia by animal species.
14	THEORECTICAL	Substances causing growth deficiency and loss of yield in poultry. Genetic toxicology.
	PRACTICAL	Taking anamnesis, sending samples to the laboratory, keeping a report and preparing a report for the determination of substances causing loss of productivity in poultry.
15	THEORECTICAL	Veterinary medicine, environmental toxicology, food pollution.
	PRACTICAL	In the determination of environmental and food pollutants sampling, sending samples to the laboratory, report keeping and report preparation.